Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

Obesity is widely known for increasing the risk of diabetes and cardiovascular disease, but its damaging effects on the ...

Researchers show that pharmacological activation of hypoxia signaling improves metabolism, limits fat accumulation, and ...

DNA can help to stimulate bone healing in a localized and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery. Scientists have developed a new ...

Researchers reveal TGF-β1 promotes scar tissue formation and restricts recovery ...

A recent discovery could transform our understanding of bone health maintenance and pave the way for potential treatments for bone diseases, including osteoporosis. Researchers at the University of ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from the Institute of Science Tokyo, Japan. Hypoxic conditions ...

Osteoporosis is a common disorder in which bones lose density and become more fragile. Over time, that raises the risk of ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...