The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, ...

Opioids such as morphine, oxycodone and fentanyl provide pain relief by binding to mu-opioid receptors, which are specialized ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off ...

Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential as a therapy for both pain and opioid use disorder. In a study published in ...

On the national stage, opioid overdose deaths fell across demographic groups. Even older Americans, whose overdose death numbers had surged earlier even as they fell for other groups, saw a 25% ...

Content warning: This story contains mention of addiction, drug use and overdose. Recovery from addiction is possible. For help, please call the confidential referral hotline, 1-800-622-HELP, or view ...

Texas A&M University Health Science Center in Bryan established a multidisciplinary opioid task force that aims to “reduce the burdens of opioid addiction, misuse and overdose on individuals, families ...

A new, synthetic opioid called N-Propionitrile Chlorphine has been involved in at least 41 deaths in East Tennessee, as ...

Nearly all Americans are aware of the U.S. opioid crisis. Overdose deaths increased sixfold between 2003 and 2023, from 12,940 to 79,358. Yearly increases have been especially steep since 2013, when ...

Nitazenes, a synthetic opioid 5 to 10 times stronger than fentanyl, are appearing in vapes and counterfeit pills — even in the Ozarks.