Brock Purdy threw a 4-yard touchdown pass to Christian McCaffrey, leading San Francisco to a 23-19 victory over defending Super Bowl champion Philadelphia in a wild-card game

Though Seattle's defense suffocated the 49ers' offense in a 13-3 win two weeks ago that clinched the NFC West, No. 1 seed and home-field advantage throughout the playoffs, San Francisco receiver Jauan Jennings claims his team "wanted' to face Seattle.

The betting market had a major reaction to the 49ers' stunning win over the Philadelphia Eagles in the Wild Card round.

The 2025-26 NFL Playoff picture is down to eight teams, and the Super Bowl favorites are becoming a bit clearer after looking at the latest sportsbooks odds. The Denver Broncos and Seattle Seahawks are coming off a bye week after earning top seeds in the AFC and NFC.

Wild Card Weekend did not let football fans down, as the Los Angeles Rams won a thriller over the Carolina Panthers, the Chicago Bears put together the greatest playoff comeback in franchise history to eliminate the rival Green Bay Packers,

The San Francisco 49ers pulled off an upset 23-19 win over the Philadelphia Eagles on the road. The 49ers will return to the West Coast to face the Seattle Seahawks at Lumen Field for a chance to advance to the NFC Championship Game.

Exactly 1,078 days had passed since the Philadelphia Eagles crushed the San Francisco 49ers in the 2023 NFC Championship game. However, given the results of their 2025 NFC Wild Card rematch, it’s safe to say that they never forgot that day.

PHILADELPHIA (AP) — Super Bowl champion Philadelphia Eagles lose 23-19 to San Francisco 49ers in wild-card round of NFL playoffs.

The first round of the NFL playoffs wrapped up in Pittsburgh on Monday night and now the one seeds in each conference get ready to join the party.

The 49ers (13-5) lost star tight end George Kittle to a torn Achilles tendon and still found a way to pull off the upset in hostile Philly, where they lost the NFC championship game three years ago after Purdy was injured in the first quarter.

The Eagles' season ends in a massive disappointment, but it couldn't have been too surprising based on how inconsistent they had been.