To test whether AT2‑derived lipids are required for metastasis, the researchers selectively deleted Fasn in AT2 cells.
Morning Overview on MSN
Prodrug lipid nanoparticle delivers IDO inhibitor and mRNA to fight tumors
Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor with the very lipids that carry IL-12 mRNA into tumors, creating a single ...
Background Colorectal cancer (CRC) exhibits increased levels of arachidonic acid-derived pro-inflammatory derivatives ...
Morning Overview on MSN
Engineered lipid nanoparticles reprogram immune metabolism to boost mRNA
Researchers are redesigning lipid nanoparticles to do more than shuttle mRNA into cells, with preclinical studies suggesting ...
The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise.
Scientists from the VIB–KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, have ...
AI has designed candidate drugs for antibiotic-resistant infections and genetic diseases. But efforts to incorporate AI into the design of lipid nanoparticles (LNPs), the revolutionary delivery ...
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