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25:54
YouTube
The Immune System Explainer
Complement System Activation
In this video, we describe how the complement system is activated. We explain the role of the classical pathway, Mannan binding lectin (MBL) pathway, and the alternative pathway in the activation process. The formation of C3-convertase in each of these pathways has been explained. The common pathway that is initiated by C5b and goes all the way ...
3.8K views
Jul 14, 2023
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✨Complement Coagulation Pathway✨ 🔸Interconnection between two major plasma cascade systems in the body: the Complement system (innate immunity) and the Coagulation system (blood clotting). 💐Complement Pathway💐 3 activation routes, all converging at the formation of C3 convertase → C5 convertase → Membrane Attack Complex (MAC, C5b–9): 🔸1.Classical pathway → triggered by Ag–Ab complexes (IgG, IgM) 🔸2.Lectin pathway → triggered by Mannose-binding lectin (MBL) 🔸3.Alternative pathway → triggere
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