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Dr Leonardo Gobbi | Endocrinologia on Instagram: "REFERÊNCIAS: Perda de gordura facial (“Ozempic face”): 1. Daneshgaran G, et al. “Ozempic Face” in Plastic Surgery: A Systematic Review. Aesthetic Surgery Journal. 2025. Disponível em: https://pmc.ncbi.nlm.nih.gov/articles/PMC12232544/ 2. Cleveland Clinic. ‘Ozempic Face’: What It Is and How to Avoid It. 2025. Disponível em: https://health.clevelandclinic.org/ozempic-face Efeito anti-inflamatório e redução do estresse oxidativo: 3. Masson W, et al.
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DrSusanBrian on Instagram: "GLP-1 RAs may have neutral or even beneficial effects on bone through several biological mechanisms. GLP-1 signaling promotes osteoblast differentiation via cAMP/PKA, PI3K/Akt, and MAPK pathways, increasing expression of osteogenic genes such as RUNX2 and osteocalcin, while simultaneously suppressing osteoclast activity through modulation of the RANK/RANKL/osteoprotegerin system and activation of Wnt/β-catenin signaling with reduced sclerostin expression. Additional a
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Shruti Patel, MD | GI Oncology on Instagram: "What the data actually show: 🔬 Preclinical data: Ivermectin has anti-cancer activity in cell culture and animal models across multiple cancers (breast, colorectal, prostate, ovarian, lung, glioma). It affects pathways like Wnt/β-catenin, PI3K/Akt/mTOR, and STAT3, leading to apoptosis and cell-cycle arrest. (Drug Des Dev Ther 2020; Cancer Chemother Pharmacol 2020; Pharmacol Res 2021) 🧪 The translational gap: These effects occur at micromolar concent
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